Me and my Daxas !!!

Helen; TY so very very much for your update. It sounds as if maybe, just maybe you and Daxas have found a match! Wouldn't that be wonderful?? And; if it does what it's hoped it will do (reduce exacerbations)....

Tell you what.... I for one will be watching for your post Spirometry and Resp visit results.

I take just one NAC (500 mg) and it's a capsule, not big at all. I have trouble swallowing pills and this is easy.

So, look for capsules. NAC has helped me - hope it does you as well.

Question?

What is NAC?

Thanks

NAC thins out the mucus. I take just one 600 mg a day although some people take two.

en.wikipedia.org/wiki/Acetylcysteine

Ah Helen, I am so sorry you had to stop taking the Daxas. I know we all had high hopes for you, but with your stomach the way it is it just is too dangerous. Did you experience any vomiting with the upset? That's what scares me the most, the possibility of aspiration with the nausea. Just not so worth it. I sure hope it doesn't take long for you to get back to feeling better. Like....right away!

I think you need a big hug......

Sue

Nycomed's co-marketing arrangement for Spain with Almirall for its new COPD drug Daxas (roflumilast) is on the face of it no big deal. Almirall can launch its own brand, but only after a delay of several months following Nycomed's own Feb 2011 launch of Daxas there. There have been doubters on the prospects for Daxas. I believe this news endorses Daxas's progress in the market internationally, as well as presaging more important developments.

Delayed launches of second, co-marketed brands are quite unusual these days. There has to be critical mass: they don't work for modest-sized products. So Almirall must think that the product is big enough to warrant taking rights to a separate brand, rather than, say, to co-promote Daxas with Nycomed.

Almirall will have been party to figures on how the Spanish launch of Daxas is going but also how the product has been faring elsewhere in Europe since launches started in Sept 2010. Almirall must have formed a positive view from Daxas's sales progress before deciding to proceed with the deal. (Like some other observers, perhaps Almirall was too sceptical about Daxas to get involved earlier.) And so in the absence of any hard figures from Nycomed so far on Daxas's progress, the Spanish news can now be taken as something of an endorsement for Daxas's progress in Europe to date.

Daxas does very much fit Almirall's existing strategy on COPD - and helps fill a gap due to delays to its aclidinium product for this indication.



There are other potentially much more important motives for the current deal on Spain - it could just be the first move in further cooperation between Nycomed and Almirall.

•It sets up Almirall for a possible project combining its aclidinium with Daxas in a fixed combination. As soon as Daxas has credibility in the market, companies with other COPD drugs are likely to be enthusiastic to combine Daxas with their drug. Such a combination could in the long term be the big prize - potentially outselling the plain components, much in the way that Advair (salmeterol + fluticasone, GSK) has done in the asthma market.
•The two companies are fairly complementary as far as European marketing strength is concerned, Northern Europe being Nycomed's strength, with Almirall stronger in Southern Europe. Further product level deals on Daxas, on other products, or even a merger of the two companies may eventually make sense.

www.glgroup.com/News/Almirall-deal-with-Nycomed-says-more-about-Daxas-prospects-than-meets-the-eye-53867.html

Well Helen;
I'm sorry to hear that. Heaven knows you "hung in there" and gave it a fair try!

Zar; were you aware that Nycomed has sold (to be completed by September) its interest in many of their product /lines (except dermatology) to the Japanese pharma company Takeda. It includes Daxas... Here's a bit more info.... www.nycomed.com/media/news-releases/2011/takeda-to-acquire-nycomed/

After coughing and I mean coughing for the past few days (since I came off Daxas) I have decided to go back on it. I just can't take the coughing which proves the Daxas did work

Will see what happens this time - of course I'm checking with the respirologist first.

Sue, I'll take that hug now

Helen,

Was coughing one of your symptoms prior to going on Daxas and then it got better while on it? I can see what a difficult decision this would be, then, as to whether to continue and experience side effects or get rid of COPD symptoms.

I have a suggestion that I think I'm mentioned to somebody else...Zofran. It is an antinausea prescription med that really helps big time. It has enabled me to be able to eat normally again and not feel sick all the time. It's a drug they give people on chemo treatments, too. I don't know if that sounds like something that would help what you are feeling, but if it is, I'd ask the dr. for it. Works really fast, too!

Good luck and know we are thinking of you and rooting for your success.
Sue

Helen,It is better that you came off Daxas.
They say that in the studies weight loss was between 2 and 2.1 kgs?.
Weight loss with Spiriva was mainly fat mass?.

helen.i have gained 6lbs from12 lbs. loss