Does GERD increase with COPD

[gerald]

Nice to see confirmed what many have already experienced. 



------------------------------------------------
Does GERD  increase with COPD?

Does gastroesophageal reflux increase chronic obstructive pulmonary disease exacerbations?
Respiratory Medicine, 04/25/2016 Clinical Article

Iliaz S, et al. – The relationship between chronic obstructive pulmonary disease (COPD) exacerbations and gastroesophageal reflux (GER) has been investigated less than asthma–GER. The authors aimed to evaluate the presence of GER in patients with COPD and its impact on exacerbations. In this study, gastroesophageal reflux was frequent in patients with COPD, but only a quarter had typical reflux symptoms. The proximal extent of reflux may trigger frequent exacerbations of COPD.

Methods

They included 24 patients with stable mild-moderate stage COPD and 19 volunteers as the control group.
They conducted a gastroesophageal reflux disease (GERD) symptom questionnaire, gastroscopy, manometry, and an ambulatory 24-h pH-impedance study.

Results

According to the GERD questionnaire, only 5 (20.8%) patients with COPD had typical GER symptoms.
According to the 24-h pH-impedance study, the mean DeMeester score (DMS) was 38.1 ± 34.6 in the COPD group and 13.3 ± .8 in the control group (p = 0.01).

The acid reflux (DMS > 14.7) rate was higher in patients with COPD than in controls (73.9% vs 26.3%, p = 0.01).

The symptom association probability positivity rate was 17.4% (n = 4) in the COPD group, which was similar to the controls (p = 0.11).
The mean proximal extension rate of reflux (Z 17 cm) was 26.4 ± 12.9% in the COPD group.
The proximal extent of reflux was positively correlated with the number of COPD exacerbations per year (p = 0.03, r = 0.448).
In the motility results, only 2 (20%) patients in the control group had a minor motility disorder.
Seventeen (70.8%) patients in the COPD group had a minor motility disorder, and 4 (.7%) had major motility disorders (p < 0.001).

mdlinx.pdr.net/nursing/news-article.cfm/6638089/0/copd-gastroesophageal-reflux-hrm-impedance-ph/next/79/?source=scroller