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Post by gerald on Dec 21, 2015 18:31:55 GMT -5
It was interesting to see that there were significant difference in blood chemistry for people with COPD. The GSH they refer to is I believe) Glutathione. Unfortunately I am not sure there is a way to determine if the difference is a cause or an effect of COPD. --------------------------------- Antioxidant nutrients in plasma of Japanese patients with chronic obstructive pulmonary disease (COPD), asthma-COPD overlap syndrome, and bronchial asthma
Background: Few studies to date have investigated the antioxidant nutrients such as vitamin C (ascorbic acid), vitamin E (α-tocopherol), retinol, and carotenoids in plasma from patients with pulmonary disease in Japan. To clarify the role of antioxidant nutrients such as vitamin C, vitamin E, retinol, and various carotenoids in plasma of Japanese patients with chronic obstructive lung diseases (COPD), asthma-COPD overlap syndrome (ACOS), and/or bronchial asthma (BA), we compared to healthy elderly controls. Methods: Ascorbic acid (AA), carotenoids (lutein, zeaxanthin, β-cryptoxanthin, α-carotene, β-carotene, and lycopene), retinol, and α-tocopherol levels in plasma were determined by using a high performance liquid chromatography. Reduced glutathione (GSH), oxidized glutathione (GSSG) in whole blood and urinary 8-OHdG were also determined. Results: Plasma AA level of COPD subjects was significantly lower than that of healthy elderly people. On the other hand, ACOS and BA subjects showed no significant difference from healthy elderly people. Moreover, plasma lycopene and total carotenoid levels and GSH content in blood were significantly lower in COPD subjects than these in healthy elderly people. However, other redox markers such as GSSG, GSH/GSSG ratio, and urinary 8-OHdG found no significant differences between COPD, ACOS, and BA compared to healthy elderly people. Conclusions: These results suggested that COPD of Japanese patients may develop partly due to oxidative stress derived from a shortage of antioxidant nutrients, especially of AA and lycopene, as well as GSH while this may not be the case in both ACOS and BA. onlinelibrary.wiley.com/doi/10.1111/crj.12436/abstract;jsessionid=1F225D195B7638ED229E6EC8DD57A3E8.f04t03 This article is protected by copyright. All rights reserved. |
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Post by judi on Dec 23, 2015 20:55:52 GMT -5
I might be worse for western countries, the traditional Japanese diet is higher in vegetables than what we eat.
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