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Post by gerald on Jul 15, 2016 13:05:44 GMT -5
An interesting study. It does cover 10000+ patients, so it is a fairly broad study. While it would need a lot more study this is a promising indication that not everything abuot cortiocosteroids is negative. It appears the full report may be available off of the website via a link for those who may be interested ----------------------------- Inhaled corticosteroids can reduce osteoporosis in female patients with COPD Background:
Whether the use of inhaled corticosteroids (ICSs) in patients with COPD can protect from osteoporosis remains undetermined. The aim of this study is to assess the incidence of osteoporosis in patients with COPD with ICS use and without. Patients and methods: This is a retrospective cohort and population-based study in which we extracted newly diagnosed female patients with COPD between 1997 and 2009 from Taiwan’s National Health Insurance (TNHI) database between 1996 and 2011 (International Classification of Diseases, Ninth Revision – Clinical Modification [ICD-9-CM] 491, 492, 496). The patients with COPD were defined by the presence of two or more diagnostic codes for COPD within 12 months on either inpatient or outpatient service claims submitted to TNHI. Patients were excluded if they were younger than 40 years or if osteoporosis had been diagnosed prior to the diagnosis of COPD and cases of asthma (ICD-9 CM code 493.X) before the index date. These enrolled patients were followed up till 2011, and the incidence of osteoporosis was determined. The Cox proportional hazards regression model was also used to estimate hazard ratios (HRs) for incidences of lung cancer. Results: Totally, 10,723 patients with COPD, including ICS users (n=812) and nonusers (n=9,911), were enrolled. The incidence rate of osteoporosis per 100,000 person years is 4,395 in nonusers and 2,709 in ICS users (HR: 0.73, 95% confidence interval [CI]: 0.63–084). The higher ICS dose is associated with lower risk of osteoporosis (0 mg to ≤20 mg, HR: 0.84, 95% CI: 0.69–1.04; >20 mg to ≤60 mg, HR: 0.78, 95% CI: 0.59–1.04; and >60 mg, HR: 0.72, 95% CI: 0.55–0.96; P for trend =0.0023) after adjusting for age, income, and medications. The cumulative osteoporosis probability significantly decreased among the ICS users when compared with the nonusers (P<0.001). Conclusion: Female patients with COPD using ICS have a dose–response protective effect for osteoporosis. www.dovepress.com/inhaled-corticosteroids-can-reduce-osteoporosis-in-female-patients-wit-peer-reviewed-article-COPD |
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Post by jarca on Jul 16, 2016 16:32:35 GMT -5
Interesting study.
I don't use a steroid inhaler, as I'm allergic to steroids.
However, In 2012 I had a bone density test & it showed that I had osteoporosis that was at the fracture point.
I had a new bone density test done in October 2015 (last year) and it said that I had Osteopenia!
I didn't know that bone density could get better!
I asked my PCP about it seems that if a person gets enough calcium that bones can improve.
I eat & drink a lot of dairy products but I don't take supplemental calcium.
I told him that I didn't take supplemental calcium that I just take a multi-vitamin & extra D3 because a blood test a few years ago said i was low of vitamin D.
He said that vitamin D helps calcium digest properly so it must be from me getting the proper amount of vitamin D!
Surprise to me!
I don't know if vitamin D is one of the vitamins that you can take too much of, but it is something that a person may want to talk to their Dr about if they have Osteoporosis or Osteopenia.
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Post by gerald on Jul 16, 2016 19:21:15 GMT -5
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Post by lavishgail on Jul 18, 2016 0:24:43 GMT -5
Yes a very good read. I take 4,ooo IC a day. My doctor said it was perfect for me so far.
Most times I was also low on my D. But I'm good now. Thanks Gerald.
Gail.
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