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Post by David on May 14, 2019 15:00:03 GMT -5
Welcome Josie
My name is David and on behave of COPD in Canada & the World I want to extend to you a warm welcome.
You will find a lot of information here .
So look around and when you are ready please join us back at the fence".
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Post by David on Apr 14, 2019 17:37:19 GMT -5
Great article.
I am the same way about hiding my struggles. I get there early or I rest before I go among other people.
The other day I was getting a hair cut. Stood outside until I got my breathing under control. When I set down she asked was I alright. I don't notice when I am slightly breathing harder but other people notice it.
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Post by David on Apr 14, 2019 17:30:45 GMT -5
Just keep taking the oil. It works for most people.
I hope some of this helps you understand more about CBD and FECO (Full Effect Cannabis Oil)
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Post by David on Apr 3, 2019 16:59:57 GMT -5
What about the earthworms. They refurbish the soil.
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Post by David on Apr 2, 2019 16:55:58 GMT -5
I don't know if this has been posted or not. First I have heard of this.
Circassia’s Duaklir Approved by FDA for Maintenance Treatment of COPD
APRIL 2, 2019 Alberto Molano
Circassia announced that the U.S. Food and Drug Administration (FDA) approved its medication Duaklir for the maintenance treatment of chronic obstructive pulmonary disease (COPD). The company plans to launch the therapy in the United States in the second half of 2019.
Duaklir is a combination of two long-acting bronchodilators: aclidinium bromide (400 mcg) and formoterol fumarate (12 mcg). It is administered twice daily, via the Pressair inhaler, a plastic device which automatically delivers the medication upon inhalation.
The two bronchodilators increase the caliber of the airways by relaxing smooth muscle tone.
Smooth muscle is a type of muscle that surrounds the airways, and that is not under voluntary control. It is regulated by sympathetic and parasympathetic nerves — parasympathetic nerves, acting through muscarinic receptors, constrict it, whereas sympathetic nerves, acting through beta-adrenergic receptors, relax it.
Aclidinium bromide is a long-acting muscarinic antagonist (LAMA); it blocks muscarinic receptors, thereby preventing airway constriction. Formoterol fumarate is a long-acting beta agonist (LABA); it activates beta-adrenergic receptors, thereby promoting airway relaxation.
The FDA approval was based on positive results from three Phase 3 studies — ACLIFORM (NCT01462942), AUGMENT (NCT01437397), and AMPLIFY (NCT02796677) — and on the phase 4 ASCENT study (NCT01966107), which specifically showed that the therapy was effective at reducing COPD exacerbations.
“With guidelines recommending combined LAMA and LABA therapy for a number of COPD patient groups, we believe Duaklir will make an important contribution to the treatment of this debilitating disease,” Michael Asmus, Circassia’s vice president, U.S. medical affairs, said in a press release.
“Duaklir’s approval is based on a broad clinical database, including data demonstrating a reduction in the risk of COPD exacerbations driven by its aclidinium component, and we look forward to making this new therapeutic option available to patients across the United States,” Asmus said.
According to Circassia, Duaklir will be the only twice-daily LAMA/LABA medication in the U.S. with COPD exacerbation data included in its prescribing information.
Steve Harris, chief executive of Circassia, said: “We are delighted with the FDA approval of Duaklir, which we believe will provide a valuable treatment option for the significant number of patients with COPD in the United States.
“The addition of Duaklir to our portfolio further strengthens our range of marketed respiratory products and we look forward to launching it in the U.S. in the coming months alongside our aclidinium monotherapy, Tudorza, as part of the significant LAMA/LABA market that is predicted to grow rapidly over the coming years.”
Tudorza is an approved medication to treat COPD symptoms.
In 2017, Circassia established a collaboration with AstraZeneca for the commercialization of Tudorza and Duaklir in the U.S. Since the end of 2018, Circassia has had the full U.S. commercial rights to both therapies.
copdnewstoday.com/2019/04/02/circassias-duaklir-approved-by-fda-for-maintenance-treatment-of-copd/
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Post by David on Mar 23, 2019 17:43:49 GMT -5
That is very sad. Sending condolences to the family.
I had to edit this when it was said Spike Mil had passed away. I thought that was his last name. Then it dawned on me that Mil could mean mother in law.
I am not all hear today.
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Post by David on Mar 19, 2019 22:16:46 GMT -5
The one on the ground is her baby. Ollie is in the stall next to April. Sometimes you can't see him.
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Post by David on Mar 18, 2019 21:50:20 GMT -5
That other giraffe is April's boyfriend. His name is Oliver and they call him Ollie. April has had 5 babies. I think the last two are Ollie's.
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Post by David on Mar 17, 2019 15:06:07 GMT -5
April had a baby boy. All seems to be well.
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Post by David on Mar 15, 2019 23:40:09 GMT -5
Gail, you need more naps. Sometimes I sleep all day. I wonder if that helps my blood pressure?
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Post by David on Mar 15, 2019 12:33:12 GMT -5
That sounds good to me. I take a lot of naps.
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Post by David on Mar 11, 2019 16:10:40 GMT -5
April the giraffe is still keeping us waiting. In last night's update, April's vet says her calf is getting into position.
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Post by David on Mar 9, 2019 21:05:45 GMT -5
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Post by David on Mar 7, 2019 21:24:56 GMT -5
That four leaf clover did the job
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Post by David on Mar 3, 2019 21:01:33 GMT -5
I put the old hard drive in and now it is running fine. go figure!!
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Post by David on Mar 3, 2019 20:56:53 GMT -5
Welcome Woodrow
My name is David and on behave of COPD in Canada & the World I want to extend to you a warm welcome.
You will find a lot of information here .
So look around and when you are ready please join us back at the fence".
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Post by David on Mar 2, 2019 20:49:41 GMT -5
I think the hard drive was about to go. It got slow and freezes a lot.
I changed hard drives and it has been running well today. We will see!!!
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Post by David on Feb 20, 2019 19:14:57 GMT -5
I believe that. Cold weather bothered me this winter a couple of times.
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Post by David on Feb 6, 2019 18:39:01 GMT -5
Welcome justanallias
My name is David and on behave of COPD in Canada & the World I want to extend to you a warm welcome.
You will find a lot of information here .
So look around and when you are ready please join us back at the fence".
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Post by David on Feb 5, 2019 22:15:39 GMT -5
I understand. You will be missed
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JO44
Feb 5, 2019 22:13:22 GMT -5
Post by David on Feb 5, 2019 22:13:22 GMT -5
Welcome Jo44
My name is David and on behave of COPD in Canada & the World I want to extend to you a warm welcome.
You will find a lot of information here .
So look around and when you are ready please join us back at the fence".
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Post by David on Jan 23, 2019 16:42:10 GMT -5
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Post by David on Jan 22, 2019 19:45:41 GMT -5
I have a good heart so I don't know how cannabis works on a heart.
I know I swear by CBD oil and FECO (Full Effects Cannabis Oil).
People just have to try it for themselves. I know it is going over big here in Florida and it is expanding. Opening 10 new dispensaries soon.
Our Governor said that in the next few months he will introduce flowers to smoke. I call them buds back in my day.
Right now we can smoke cannabis oil in a vaping pen. I don't smoke so I put the drops under my tongue.
I am still having good luck with the cannabis. I caught a chest cold a few weeks ago and that really set me back. Funny how an exacerbation always seem to set one back and you have to work hard to get back to where you were. I am living in a slightly different climate now and I can tell it does effect me. The rain and the cold weather is not good for me. I didn't get this much rain and cold when I lived on the beach. Hopefully I will adjust to my new surroundings.
700 medical cannabis studies sorted by disease.
hamptonbaymedicalnews.com/2018/09/04/700-medical-cannabis-studies-sorted-by-disease-medical-marijuana-uses-700-medical-marijuana-clinical-studies-and-papers/
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Post by David on Jan 2, 2019 22:32:58 GMT -5
Nothing, I already quit smoking and drinking.
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Post by David on Dec 25, 2018 16:12:46 GMT -5
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Post by David on Dec 24, 2018 20:26:09 GMT -5
Last Seen Brasília, Brazil
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Post by David on Dec 24, 2018 16:47:43 GMT -5
Hemp can do everything crude oil and cotton can do and more. That's amazing to me.
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Post by David on Dec 20, 2018 22:19:10 GMT -5
Welcome friend of life...
My name is David and on behave of COPD in Canada & the World I want to extend to you a warm welcome.
You will find a lot of information here .
So look around and when you are ready please join us back at the fence".
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Post by David on Dec 20, 2018 13:55:03 GMT -5
That is great news.
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Post by David on Dec 20, 2018 13:48:59 GMT -5
PRESIDENT TRUMP SIGNS THE FARM BILL INTO LAW TODAY AT 2:30 pm
Today is the day! President Trump will sign the 2018 Farm Bill into law at 2:30 pm today in a White House bill signing ceremony. The bill fully removes hemp from the Controlled Substances Act and authorizes states to regulate hemp farming.
You can watch the ceremony live on C-SPAN.
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